Acetazolamide is a drug used by mountain climbers for short per... | Filo
Acetazolamide is a drug used by mountain climbers for short per... …
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Aazer Nawab on Instagram: "Acetazolamide (a carbonic anhydrase inhibitor) is one of the most useful drugs for treating metabolic alkalosis, especially when it is chloride-responsive and the patient is volume overloaded or cannot tolerate excess chloride. How Acetazolamide Works It corrects metabolic alkalosis through three main mechanisms: Increases Renal Bicarbonate Excretion •Inhibits carbonic anhydrase in the proximal tubule •↓ Reabsorption of HCO₃⁻, causing bicarbonaturia •Serum bicarbonate
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