Feb 10, 2021 · ST2 itself may participate in the pathophysiological process of each component of MetS by affecting the inflammatory and immune response, thus taking part in the occurrence and …

Jan 14, 2025 · Soluble ST2 (sST2) is released in response to vascular congestion, inflammation, and pro-fibrotic stimuli.

4 days ago · ST2 (short-chain receptor 2, also known as the IL-33 receptor) is an important immune system molecule widely present in various immune cells and other cell types. The binding of the ST2 …

Jul 17, 2025 · Soluble growth stimulation-expressed gene 2 (sST2) is a promising cardiovascular biomarker, but its prognostic value in COVID-19 remains unclear. Methods: This retrospective cohort …

Apr 2, 2015 · Recent studies have demonstrated soluble ST2 to be a strong predictor of cardiovascular outcomes in community-based populations free of cardiovascular disease. This report reviews the …

Jul 1, 2018 · ST2 is a member of the interleukin 1 receptor family and exists in two forms, a trans-membrane receptor (ST2L) as well as a soluble decoy receptor (sST2).2 The ligand of ST2 is …

Jan 9, 2014 · ST2, an IL-1 receptor family member with transmembrane (ST2L) and soluble (sST2) isoforms, was originally described in the context of inflammatory and autoimmune diseases.

The soluble form of ST2 is a decoy receptor that inhibits beneficial cardioprotective effects of IL-33; such inhibition results in cardiac hypertrophy, myocardial fibrosis, and ventricular dysfunction. …

Aug 3, 2024 · Soluble ST2 (sST2) is a novel biomarker that is closely associated with different CVDs. Its low reference change value makes it suitable for continuous measurement, unaffected by age, …

Nov 4, 2022 · As an interleukin (IL)-1 receptor family member, scientists found that when circulating soluble growth stimulation expressed gene 2 (sST2) is low, its ligand, IL-33, will bind to ST2L to exert …