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  1. ENTYVIO is an appropriate first-line advanced therapy option for my patients with moderately to severely active UC or Crohn’s because of its safety and efficacy data, especially in either TNF-naïve …

  2. BACKGROUND Vedolizumab (Entyvio) is a humanized monoclonal antibody utilized for the treatment of Crohn’s disease and ulcerative colitis in adult patients. Vedolizumab binds to alpha-4-beta-7 integrin …

  3. In clinical trials with intravenous ENTYVIO at doses ranging from 0.2 to 10 mg/kg and 180 to 750 mg (which include doses outside of the recommended dose) in healthy subjects and in patients with …

  4. Vedolizumab treatment persistence and safety in a 2‐year data …

    Vedolizumab was shown to be effective and safe for patients with ulcerative colitis (UC) or Crohn's disease (CD) in the GEMINI phase 3 and long‐term safety (LTS) studies. To report treatment …

  5. Ulcerative Colitis: The AGA (2024) and the ACG (2025) have clinical practice guidelines on the management of moderate to severe UC.4,5 In moderate to severe disease, systemic corticosteroids …

  6. Entyvio Prescribing Information - Clinical Considerations for ...

    Apr 15, 2025 · Building on these results, Entyvio —the branded formulation of vedolizumab—has emerged as a leading treatment for IBD. By leveraging a gut-selective mechanism, Entyvio reduces …

  7. ENTYVIO® (vedolizumab) for Crohn's Disease or Ulcerative Colitis

    ENTYVIO is a biologic treatment for moderate to severe Crohn's disease (CD) or ulcerative colitis (UC). See Safety and Prescribing Information.

  8. AGA overhauls UC treatment pathway: early, high-efficacy therapies …

    Mar 27, 2025 · Takeda’s Entyvio remains prominent due to its favourable efficacy and safety profile. Biosimilars of infliximab, adalimumab, and ustekinumab are endorsed as interchangeable, and …

  9. Clinical use of vedolizumab subcutaneous formulation in …

    Aug 16, 2025 · Introduction Vedolizumab is an advanced therapy indicated for the treatment of moderately to severely active Crohn’s disease (CD) or ulcerative colitis (UC). After induction with …

  10. Executive Summary - Clinical Review Report: Vedolizumab (Entyvio

    NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. Clinical Review Report: Vedolizumab (Entyvio SC): Takeda Canada Inc. Indication: For the treatment of adult …