Family Destinations Guide

This Tiny Illinois Deli Serves The Most Ridiculously Overstuffed Sandwiches

Tony’s Italian Deli & Grocery in Chicago exists to give you that exact experience, and somehow, you’ll be grateful for it.
Crypto Briefing

Gokul Rajaram: Owning the full stack is essential for scaling, product excellence drives success, and investors must focus on long-term potential | 20VC

Companies face challenges in scaling within competitive markets without full-stack ownership. Full-stack ownership provides a ...

How the Guy Who Invented V-Grades Won Back His Bouldering Mojo

Conversations with bouldering legend John "Verm" Sherman and filmmaker Dawn Kish about their new award-winning film 'Old Man ...
eLife

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...