The results are transforming how scholars understand human history. By analysing parchment, researchers are uncovering ...

Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

A DNA-based barcoding assay can now quantify, in living mice, how much genetic cargo escapes cellular disposal versus how much is degraded. Measurements from the assay guided the design of lipid ...

Scientists have taken a major step toward mimicking nature’s tiniest gateways by creating ultra-small pores that rival the dimensions of biological ion channels—just a few atoms wide. The breakthrough ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

Vinyl records and DNA sequencing might not seem like they have a lot in common, but in a video by PacBio, adjunct assistant professor of Biology Andor Kiss made a case for their similarities. PacBio ...

Othram scientists work in a Texas-based lab to build genealogical profiles of missing people and crime suspects. In 1992, Pittsburgh Police and River Rescue recovered a man’s body from the Allegheny ...

For decades, the Golden State Killer avoided capture despite leaving DNA at multiple crime scenes. Traditional databases failed, fingerprints led nowhere, and the case went cold. Everything changed ...

When scientists sequence tumor DNA, they typically find small amounts of genetic code from bacteria, viruses and fungi – microorganisms that, if actually present in tumor tissues, could influence how ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

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