XDA Developers on MSN

Google's Gemma 4 isn't the smartest local LLM I've run, but it's the one I reach for most

Google's newest Gemma 4 models are both powerful and useful.
XDA Developers on MSN

I used my local LLM to sort hundreds of gaming clips, and it was the laziest solution that worked

I tried training a classifier, then found a better solution.
eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
AHA/ASA Journals

Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...
eLife

Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...
The Manila Times

iDenfy launches MCP server for AI powered KYC, KYB, and AML integrations

Developers can use ChatGPT, Claude, Gemini, Cursor, and other AI assistants to access iDenfy’s live documentation, generate ...
Beirut Time

Mapping convergent regulators of melanoma drug resistance by PerturbFate

A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...