eLife

Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...
GitHub

PyCIL: A Python Toolbox for Class-Incremental Learning

Welcome to PyCIL, perhaps the toolbox for class-incremental learning with the most implemented methods. This is the code repository for "PyCIL: A Python Toolbox for Class-Incremental Learning" [paper] ...

OFSS Bihar class 11th admission 2026: Application ends on April 18; check eligibility and direct link here

The Bihar School Examination Board (BSEB) is closing applications for Class 11 admissions for the 2026-28 academic session on ...
eLife

Gβγ engages PLCβ3 at multiple sites to reorient and facilitate its activation

EM, biochemical, and cell-based assays to examine how Gβγ interacts with and potentiates PLCβ3. The authors present evidence for multiple Gβγ interaction surfaces and argue that Gβγ primarily enhances ...

Class 11 admissions to begin on April 10, part 1 open before SSC results

Class 11 admissions for 2026-27 start April 10 via a centralized online system. Part 2 opens post-Class 10 results in June, aiming for a smoother process.