Mapping mutations at scale in a single gene reveals new neurodevelopmental condition

The ability of different genetic variants—changes to one or more building blocks of DNA—to cause disease, and to what extent, ...
GEN - Genetic Engineering and Biotechnology News

Forecasting Protein Aggregation with an Improved Algorithm

Barcelona researchers have created an algorithm for studying protein aggregation and mutating proteins from AlphaFold.
IEEE

A Multi-Fidelity Genetic Algorithm for Hyperparameter Optimization of Deep Neural Networks

Abstract: Hyperparameter optimization on Machine Learning models is crucial for their correct refinement. For complex big models (such as Deep Learning models), in which a single training model is ...
IEEE

A Hybrid Constructive Genetic Algorithm (HCGA) for the Vehicle Routing Problem With Time Windows in Logistics Optimization

Abstract: The Vehicle Routing Problem with Time Windows (VRPTW) is paramount in elevating operational efficiency, driving cost reductions, and enhancing customer satisfaction. This problem has ...
The Lancet

Shared genetic architecture between sleep traits and cardiometabolic diseases

aDepartment of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China bNational Clinical Research Center for Geriatric Disease (Xiangya Hospital), Central South University, ...