A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and a decline in mental ...

Glucocorticoid-induced osteoporosis (GIOP) remains a major clinical challenge, affecting up to half of patients receiving long-term glucocorticoid therapy. Excessive oxidative stress and impaired ...

At first sight, stromatolites may seem unremarkable. The stromatolite formations found in Shark Bay, Western Australia, do ...

Damien Chua, PhD student; Liu Yu Xuan, Research Associate; Joseph Kim, PhD student; Cheng Hong Sheng, Senior Research Fellow; and ...

Glioma is a tumor of the central nervous system that originates from glial cells, which support neurons in the brain. In the ...

Background: Exercise unmasks limitations in multi-organ system reserve capacity characteristic of heart failure with preserved ejection fraction (HFpEF). However, the metabolic and genetic ...

Genomic analysis reveals squid and cuttlefish evolved in deep oceans, survived mass extinction in refuges, and later rapidly diversified, following a “long fuse” evolutionary pattern.

The correlation between smoking and neurodegeneration is well-documented, with one study from 2011 finding that heavy smoking in midlife was associated with a greater than 100% increase in risk of ...

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients. The study focuses on the adenomatous ...

A precision cancer strategy that selectively kills tumour cells while leaving healthy tissue intact may be within reach for the majority of colorectal cancer patients, according to new research ...

UChicago PME researchers trace a new pathway of disruptive chemical messages that could help explain why heavy smokers face ...