The complete genome for the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they?

The complete genome of the tuberculosis bacterium was sequenced and published in 1998. Since then, scientists have deciphered about two-thirds of TB's genes. Or have they?

When a wound does not heal properly, it leaves a scar. Similarly, mutations – which are permanent changes to genetic code – ...

Researchers at The Institute of Cancer Research, London, working with Merck KGaA, have developed the first potent small-molecule inhibitors of DHX8, an enzyme involved in pre-mRNA splicing. The ...

Radiopharmaceutical therapy (RPT) delivers protracted, low absorbed dose rate radiation over time, with cellular DNA repair ...

Our DNA is under constant threat. Chemicals, radiation and the everyday errors of cell division all damage it, and if left unrepaired, this can lead to diseases such as cancer. Cells invest heavily in ...

In a recent study, scientists devised a way of reversing the buildup of compounds that lead to some age-related diseases. By K. R. Callaway The same chemical process that turns a baking cake golden ...

Heidi Ledford reports for Nature from Seattle, Washington. Scientists have exploited a peculiar CRISPR enzyme so that it fights cancer by shredding the DNA in cancer cells, causing them to ...

A reaction scheme shows N-epsilon-carboxymethyl-lysine in a polypeptide being hydrolyzed to form unmodified lysine (still in a peptide) and glyoxylic acid. N ε-carboxymethyllysine can form after a ...