Key to Invitrogen's Gateway technology is the "entry clone," which contains a fragment of interest in a recombinase-ready plasmid. Researchers can quickly and efficiently move between expression ...

Johns Hopkins University School of Medicine alumnus and former faculty member Hamilton O. Smith, whose 1978 Nobel Prize-winning discovery of restriction enzymes revolutionized genetic engineering, ...

Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...

When Herbert Boyer of the University of California and Stanley Cohen of Stanford University found a way to recombine DNA molecules in test tubes using restriction enzymes, 1 they crossed the ultimate ...