This film creatively illustrates the process of protein synthesis through dance, symbolizing the assembly of amino acids into proteins. It explains how genes encode instructions for amino acid ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids, but cannot simply accumulate inside the cell forever. Once they have done their ...

Three dimensional cryo-EM structure of VCP (blue and purple) bound to three VCPIP1 promoters (red, orange, and yellow). Healthy cells are constantly breaking down proteins and building up new ones ...

A study on how aging impacts the brain in killifish has found that getting old selectively impairs the production of some key DNA- and RNA-binding proteins. And this change contributes to hallmarks of ...

Ribosomes are composed of two subunits, the small and large subunits, each containing specific rRNA molecules. The main types of rRNA include: Small Subunit rRNA: In prokaryotes, the small subunit ...