A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

A team of researchers has constructed the most detailed single-cell map of the adult human prostate to date, cataloging more ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...

This Research Topic is the second volume of the “Unraveling Breast Cancer Complexity: Insights from Single-Cell Sequencing and Spatial Transcriptomics” ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as heart, skin or liver tissue. These snapshots provide insights into how spatial ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.

Single-cell RNA sequencing has transformed biology by showing which genes are active in individual cells. However, this approach requires cells to be removed from their natural environment, erasing ...