No gene acts alone: interacting variants and protein partnerships can worsen, mask or even rescue disease risk, demanding ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Genetic variants believed to cause blindness in nearly everyone who carries them actually lead to vision loss less than 30% ...

New research reveals that certain brain tumors may originate silently within normal brain cells long before a tumor forms.

Dozens of people in the United States have caught bird flu from animals this year, but there's no evidence that the viral disease has spread from one person to another. However, a single mutation in ...

Genetics is rarely as straightforward as a single gene driving a lone health outcome. But a new study has uncovered what could be a rare exception. Changes to just one gene, called GRIN2A, have now ...

For decades, psychiatrists have told patients that conditions like schizophrenia and severe depression arise from a tangled mix of genes and life experience, with no single culprit to blame. Now ...

The need to change regulations around gene-editing treatments was endorsed in November by the head of the US Food and Drug ...

Hypertension is an important public health problem affecting more than 50 million individuals in the US alone. The most common form, essential hypertension, results from the complex interplay between ...