If you cast a wide enough net, you’ll find what looks like a prize-winning fish. But you’ll also catch a lot of seaweed, plastic debris, and maybe even a dolphin you didn’t mean to bring in. Such is ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

I contend that there is a better way to correct the misuse of tests for statistical significance than by dispensing with them altogether (see V. Amrhein et al. Nature 567, 305–307; 2019). The ...