Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

The coronavirus disease 2019 (Covid-19) pandemic has highlighted the crucial role of randomized trials in guiding clinical practice and the need for designs that provide rapid evaluation of multiple ...

Microwave ablation plus chemotherapy significantly improves progression-free survival in advanced NSCLC without increasing toxicity compared to chemotherapy alone. The combination treatment leverages ...

Randomization Techniques (60 minutes): In this workshop, the rationale behind randomized experiments will be explained. Descriptions of commonly utilized randomization algorithms will be presented, ...

An expert from the FDA explained the benefits and limitations of these two clinical trial formats and how the cancer field can learn from both. The use of single-arm trials, in which all patients ...