Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...

Booster Therapeutics (Germany) focuses on developing small-molecule proteasome activators for neurodegenerative disease using ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the complete set of proteins in an organism) that was previously thought ...

Immunotherapy has transformed the field of cancer medicine. It has extended survival rates, reduced toxicity, and, in some cases, completely eradicated the tumor. Immunotherapy is a form of cancer ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

Chronic diseases such as type 2 diabetes and inflammatory disorders are a major cause of disease burden and deaths around the world, but their treatment has proven difficult because there may not be ...

If we can take it apart, we can stop these diseases before they take hold." Though no drugs currently target RAP proteins, Le Roch's lab is working toward solving the 3D structure of these RNA-protein ...