Thrombocytopenia, inherited as a dominant trait, was present in three generations of a kindred. The clinical picture was quite similar to that of idiopathic thrombocytopenic purpura, but ...

IMPAIRMENT of the hemostatic mechanism is a common experience in active disease of the liver. Several recent reports 1–4 have stressed the multiplicity of plasma clotting factors that may be deficient ...

Thrombocytopenia absent radius (TAR) affects the radius — the long, thin bone in the forearm — and platelet function. This defect commonly appears at birth or within the first few years of life.

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Gut microbes alter platelet function and risk of blood clot-related illnesses like heart attack and stroke, researchers have demonstrated -- for the first time -- through a combination of both ...

The document follows two earlier consensus documents, released in 2013 and 2016. Dominick Angiolillo, MD, PhD (University of Florida College of Medicine – Jacksonville), senior author of the paper, ...

Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...

Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and ...

WASHINGTON, DC—Additional evidence, this time from a phase IIb trial in healthy people ages 50 to 80, supports that bentracimab (PhaseBio) provides a near-immediate reversal of ticagrelor’s ...