Fluid management. Fluid resuscitation is the first step in DKA therapy. 3 The total fluid deficit is estimated to be 3.0 to 6.0 L in DKA. 5 Fluid is replaced as a crystalloid bolus to improve GFR ...

From the Adult Diabetes and Clinical Research Sections, Joslin Diabetes Center, Harvard Medical School. Approved May 10, 2016; updated April 24, 2018. For the Figure and Tables, download the PDF at ...

Diabetic ketoacidosis is a common severe complication of diabetes, which develops when the body can't produce enough insulin.

Diabetic ketoacidosis (DKA) and hyperglycaemic hyperosmolar state (HHS) are serious acute metabolic complications of diabetes mellitus, representing points along a spectrum of hyperglycaemic ...

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Diabetic ketoacidosis is a common severe complication of diabetes, which develops when the body can't produce enough insulin. During DKA the body starts breaking down fat, causing a buildup of acids ...

When cells cannot access glucose as an energy source, the body turns to alternative fuels, such as fat. This process produces substances known as ketones, which can accumulate in blood and urine. In ...

Despite these losses, the increased delivery of potassium to the ECF from the intracellular space usually causes the serum concentration of potassium to be normal and, in some cases, high. This ...

Researchers show that using continuous glucose monitors can help measure glucose accurately during DKA and potentially prevent ICUs from being overwhelmed. Diabetic ketoacidosis is a common severe ...