Vol. 57, No. 2, SPECIAL REVIEW SERIES ON 3D ORGANOTYPIC AND ORGANOID CULTURE MODELS (FEBRUARY 2021), pp. 133-147 (15 pages) The human kidney, which consists of up to 2 million nephrons, is critical ...
aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...
Researchers developed tubuloids from adult kidney cells. When exposed to cisplatin, the model replicated key steps in the chronic kidney disease progression, including DNA damage, cellular senescence, ...
A research effort led by scientists from the Keck School of Medicine at the University of Southern California (USC) has led to the development of more mature and complex lab-grown kidney progenitor ...
This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...
“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...