CRISPR-Cas9 is widely used to edit the genome by studying genes of interest and modifying disease-associated genes. However, this process is associated with side effects including unwanted mutations ...

PHILADELPHIA— A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods. The approach ...

Researchers have developed a single genome-editing strategy, known as PERT, that could potentially treat various diseases caused by nonsense mutations.

A novel genome editing technique, NICER, is based on the creation of multiple nicks in single DNA strands by nickase. The method can correct heterozygous mutations using two mechanisms: multiple nicks ...

Researchers have opened a transformative chapter in agricultural biotechnology by unveiling virus-induced genome editing (VIGE) techniques for Solanaceous crops, a group that includes tomatoes, ...

Chemists have developed an efficient skeletal editing method for frequently used heteroaromatic structures. The technique could serve as a means to chemically modify biologically active compounds.