Based on this concept, the team developed a high-throughput platform that combines yeast surface display with chemoselective protein modification to screen diverse crosslinkers and millions of protein ...

A paper titled "Functional implications of unusual NOS and SONOS covalent linkages found in proteins," by Matthew D. Lloyd, Kyle S. Gregory, and K. Ravi Acharya, from the University of Bath Department ...

Materials with permanent, nanometre-scale pores exhibit specific properties and functions that would be impossible to attain in non-porous materials. Progress in chemistry and materials science over ...

Chemical probes that form a covalent bond with a protein target often show enhanced selectivity, potency and utility for biological studies. Despite these advantages, protein-reactive compounds are ...

L1, termed IB101, which was found to form a defined binding pocket that precisely positions the active moiety in a reactive conformation.

A team led by principal investigators Bobo Dang and Ting Zhou at Westlake University/Westlake Laboratory have developed a ...