This article and associated images are based on a poster originally authored by Sophie O’Neil, Kyle Thompson, Rita Pereira, Emily Russell and Stuart McElroy and presented at ELRIG Drug Discovery 2025 ...

Jonathan from the Institute of Human Anatomy uses real human brain dissections to show where psychedelic compounds bind and how they alter perception. The video traces oral ingestion (oral cavity → ...

Serotonergic psychedelics, such as psilocybin and LSD, are also commonly referred to as hallucinogens because at higher "trip-inducing" doses (as opposed to microdoses), these drugs typically trigger ...

Signals in our brain are not always processed in the same way: certain receptors modulate these mechanisms, influencing our mood, perception, and behavior in various ways. One of these is the 5-HT2A ...

STUART, Fla.--(BUSINESS WIRE)--Cognigenics, a pioneering company in RNA-based therapeutics for neuropsychiatric conditions and neurocognitive disorders, announced the publication of its latest ...

Co. Ltd. has resulted in the discovery of new 5-HT2A receptor agonists potentially useful for the treatment of depression, anxiety, bipolar, eating and obsessive-compulsive disorders, chronic pain, ...

Psychedelics activate the 5-HT2A receptor, upregulate brain-derived neurotrophic factor, and enhance synaptic plasticity, leading to therapeutic potential for stress and psychiatric disorders. Credit ...

A serotonin-specific receptor can determine how important visual stimuli are perceived. This explains the effects of certain drugs and could help in understanding psychiatric diseases. Signals in our ...

Up to 90% of people with dementia develop at least one behavioral or psychological symptom, such as psychosis, anxiety or agitation/aggression, which often overlap and worsen both patient quality of ...